A study has shown that mammograms increase the risk of breast cancer, according to The Daily Mail, the Irish Independent and all the other papers who picked up from the wires a rehash of a scientific study published in the Journal of Clinical Oncology.The risk from mammograms was greatly increased for women with two mutated genes which put them at a higher risk of cancer, they reported.
It isn’t true. The study showed that chest X-rays, taken while breast tissue is still developing in women with the genes, can increase the risk by up to 54%.
The study of 1,600 women did not analyse the risk from mammograms. Despite the study’s authors pointing this out when they realised their work was being misrepresented, the papers went ahead with their scare story anyway.
The chest X-rays might be taken in childhood for spinal abnormalities, for instance. Women from families prone to breast cancer should think about having MRI or other scans that aren’t X-rays, the International Agency for Research on Cancer, in Lyon, concluded.
“Exposure to chest X-rays (not-including mammograms, which were assessed in a subsequent part of the questionnaire) was assessed first as ever or never.”
Note the “not-including mammograms”. The authors concluded that because there was too much bias in reporting of having mammograms, another study specifically about mammograms was needed.
In fact, an advisory went out on the wires later the same day that the wires put out the original, incorrect, version of the story. It said something to the effect that “mammograms do not increase the risk of breast cancer in women with the genes, according to this study”.
Despite having plenty of time to do so before their print deadlines, the newspapers did not correct their incorrect, less sexy version of the story.
Or else they didn’t see the advisory.
Here’s what the Mail wrote.
And here’s the abstract of the scientific paper.
And here’s a quote from the full paper, which I had to get through nefarious means (thanks Mr D):
“The results presented here also raise the issue of the potential risks from mammographic screening, which is often used to screen BRCA [the faulty genes] carriers starting from their early 30s. Unfortunately, the analysis of the effect of mammographic exposure on BC [breast cancer] risk is likely to be biased in retrospective studies because of its obvious relatoinship to diagnosis, and accordingly, a prospective study of mutation carriers with detailed mammographic exposure history with adjustment for confounding variables (eg, family history) is a priority.”
So the upshot is:
- Chest X-rays when young increase risk of breast cancer in women who are prone to it.
- The people who did the study don’t know if mammograms do as well so we need to do that research.
- If you are a newspaper and a later advisory comes out which spoils your scare story, ignore it, especially if your story is about women’s breasts.